Papain is naturally occurring enzyme, obtained from latex of fruit of PAPAYA (Carica papaya Latex). The enzyme Papain is obtained by drying papaya latex by suitable method viz; sun drying, tray drying, spray drying etc. spray drying gives a fine powder, which dissolves easily in water to provide a solution of high proteolytic activity.
Papain is widely used for replacement therapy in pathological conditions in which the concentration of bile acids in upper intestine is low such as biliary fistula, disease of the ileum, and hepatic or extra - hepatic cholestasis.
Papain is an excellent fibrinolytic and caseinolytic enzyme, which in combination with amylase and lipase proves to be formidable digestive aid.
It is also used for preparation of medicines such as ointments for debridement of wounds, inflammatory processes and also for cleaning solutions for soft contact lenses.