Metesoakzyme is a leather soaking enzyme to be used in leather beam-house processes. Metesoakzyme is specially designed for soaking if skins and hides. It specifically removes the intrafibrillary protein materials that cement fibers to allow maximum re-hydration. It also removes connective tissue proteins, thus, loosening flesh and adipose tissue stuck to hides. The protease enzyme present in Metesoakzyme, removes unwanted protein material like albumin and mucin, without damaging the collagen; whereas the lipase enzyme disperses fatty substances and oils, enhancing re-hydration and removal of adipose tissue. Metesoakzyme is a ready-to-use formulation of enzyme and other ingredients for high-performance soaking, giving smooth grain, flat growth marks and assist in easy removal of hair and scud in the subsequent processes like dehairing, liming, bating and chrome tanning. Metesoakzyme reduces chemical consumption and water effluent problems. Wetting agents and detergents can be avoided while using with Metesoakzyme.